Calcineurin-Modulated Antimicrobial Peptide Expression Is Required for the Development of Helicoverpa armigera

Calcineurin-Modulated Antimicrobial Peptide Expression Is Required for the Development of Helicoverpa armigera

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Helicoverpa armigera is a universal pest around the world that has been extensively used as a model organism for agricultural pests.Calcineurin (CAN) is an important Ca2+-dependent phosphatase that is participated in various biological pathways.Here, we revealed that CAN inhibition significantly arrested H.armigera larval development by reducing larvae Wrestling - Shoes - Mens weight, prolonging development time and reducing pupate rates.Furthermore, CAN serves as an immune activator and regulates antimicrobial peptide (AMP; cecropin D, attacin, and gloverin) expression by binding with relish transcript factor in H.

armigera.This Oils study provides a potential target to control H.armigera by using synergistic agents for pesticides or plant-mediated RNA interference technology.